A Critical Review on the Role of Camel Milk in Multiple Health Outcomes
DOI:
https://doi.org/10.18311/jnr/2023/33998Keywords:
Camel’s Milk, Chronic Disease, Protein, Therapeutic PropertiesAbstract
Camel milk has been demonstrated to be effective in treating a broad range of illnesses. Camel’s milk is regarded to have therapeutic properties because of its unique composition. Some people consider camel milk to be a precious commodity. White camel milk is made by combining fat and water. Several clinical studies have shown that camel’s milk is effective in treating a broad variety of diseases, including chronic ones. Most of the medicinal advantages of camel milk are included in this study. Camel Milk ingredients and qualities are similar to those found in mother’s milk, making it superior than cow’s milk. Insulin-like and protective proteins are found in abundance, along with lactose, which is the primary carbohydrate. It has anti-tumor qualities, and the robust immune system components assist combat disorders, including diabetes, autism, and diarrhea. It has been used by Nomads and Bedouins (Arabian tribals) for millennia because of these properties. The main objective of this review article is to demonstrate its various pharmacological roles. Camel’s milk is regarded as a vast medicinal property, as it contains a unique composition of bioactive moieties like lactose, proteins (Lactoferrin, Lactoperoxidase, Insulin, Casein), vitamins (A, B1, B2, C, D, E), minerals (Calcium, phosphorus, magnesium, iron, zinc and copper) carbohydrates etc. Most of the medicinal advantages of camel milk are covered in this paper, like its role in the management of autism, Crohn’s disease, allergic conditions, Hepatitis B and C, as antiviral and antibacterial agent. Hence, this study was planned to collect the updated latest information regarding use of camel’s milk, which will be very beneficial in the field of medicines and managing various ailments for the benefit of mankind.
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Copyright (c) 2023 Saumya Das, Avijit Mazumder, Anchit Dogra (Author)
This work is licensed under a Creative Commons Attribution 4.0 International License.
Accepted 2023-07-24
Published 2023-11-10
References
Gader AGMA, Alhaider AA. The unique medicinal properties of camel products: A review of the scientific evidence. Journal of Taibah University Medical Sciences. 2016; 11(2):98-103. https://doi.org/10.1016/j.jtumed.2015.12.007 DOI: https://doi.org/10.1016/j.jtumed.2015.12.007
Zibaee S, Hosseini SMa-R, Yousefi M, Taghipour A, Kiani MA, Noras MR. Nutritional and therapeutic characteristics of camel milk in children: A systematic review. Electron Physician. 2015; 7(7):1523-8. https://doi.org/10.19082/1523 DOI: https://doi.org/10.19082/1523
Sisay F, Awoke K. Review on production, quality and use of camel milk in Journal of Fisheries and Livestock Production. 2015; 3:145. https://doi.org/10.4172/2332-2608.1000145 DOI: https://doi.org/10.4172/2332-2608.1000145
Gizachew A, Teha J, Birhanu T. Ethiopia Nekemte. Review on medicinal and nutritional values of camel milk. Nature and Science. 2014; 12:35.
Asresie A, Yusuf M. Traditional consumption, therapeutic value and its derived dairy products of dromedary camel (Camelus dromedaries) milk in Somali regional state, Eastern Ethiopia: A review. Global Journal of Animal Scientific Research. 2014; 3:240-6.
Kumar YK, Rakesh K, Lakshmi P, Jitendra S. Composition and medicinal properties of camel milk: A review. Asian Journal of Dairy and Food Research. 2015; 34:83-91. https://doi.org/10.5958/0976-0563. 2015.00018.4 DOI: https://doi.org/10.5958/0976-0563.2015.00018.4
Konuspayeva G, Faye B, Loiseau G. The composition of camel milk: A meta-analysis of the literature data. Journal of Food Composition and Analysis. 2009; 22:95-101. https://doi.org/10.1016/j.jfca.2008.09.008 DOI: https://doi.org/10.1016/j.jfca.2008.09.008
Gul W, Farooq N, Anees D, Khan U, Rehan F. Camel Milk: A boon to mankind. International Journal of Research in BioSciences. 2015; 3:23-9.
Korashy HM, El Gendy MA, Alhaider AA, El-Kadi AO. Camel milk modulates the expression of aryl hydrocarbon receptor-regulated genes, Cyp1a1, Nqo1, and Gsta1, in murine hepatoma Hepa 1c1c7 cells. Journal of Biomedicine and Biotechnology. 2012; 2012:782642. https://doi.org/10.1155/2012/782642 DOI: https://doi.org/10.1155/2012/782642
Musaad AM, Faye B, Al-Mutairi SE. Seasonal and physiological variation of gross composition of camel milk in Saudi Arabia. Emirates Journal of Food and Agriculture. 2013; 2(8):618-24. https://doi.org/10.9755/ejfa.v25i8.16095 DOI: https://doi.org/10.9755/ejfa.v25i8.16095
Al-Juboori AT, Mohammed M, Rashid J, Kurian J, El-Refaey S Nutritional and medicinal value of camel (Camelus dromedarius) milk. Second International Conference. 2013; 170(12):221-32. https://doi.org/10.2495/FENV130201 DOI: https://doi.org/10.2495/FENV130201
Sharma C, Singh C. Therapeutic value of camel milk-A review. Advanced Journal of Pharmacie and Life Science Research. 2014; 3:7-13.
Farah Z, Streiff T, Bachmann MR. Manufacture and characterisation of camel milk butter. Milchwissenschaft. 1989; 44(7):412-14.
Yagil R. Camels and camel milk. FAO Animal Production and Health. Paper No. 26. Food and Agriculture organization, Rome, Italy; 1982.
Ramet JP. The technology of marketing cheese from camel milk (Camelus dromedarius). FAO Animal Products and Health and Health Paper. 2001; 113:31-33.
Vikas M, Farah Z. Manufacture of cheese from camel milk. Report on field studies in Kenya, ETH Zurich, Switzerland; 1991.
Abbas S, Ashraf H, Nazir A, Sarfraz L. Physico-chemical analysis and composition of camel milk. International Research. 2013; 2:85-98.
Konuspayeva G, Lemarie E, Faye B, Loiseau G, Montet D. Fatty acid and cholesterol composition of camel’s (Camelus bactrianus, Camelus dromedarius and hybrids) milk in Kazakhstan. Dairy Science and Technology. 2008; 88:327-340. https://doi.org/10.1051/dst:2008005 DOI: https://doi.org/10.1051/dst:2008005
Omar RH, Eltinay AH. Microbial quality of camel’s raw milk in central and southern regions of United Arab Emirates, Emirates Journal of Food and Agriculture. 2008; 20:76-83. https://doi.org/10.9755/ejfa.v20i1.5182 DOI: https://doi.org/10.9755/ejfa.v20i1.5182
Guo HY, Pang K, Zhang XY, Zhao L, Chen SW, et al. Composition, physiochemical properties, nitrogen fraction distribution, and amino acid profile of donkey milk. Journal of Dairy Science. 2007; 90:1635- 43. https://doi.org/10.3168/jds.2006-600 DOI: https://doi.org/10.3168/jds.2006-600
Shamsia SM. Nutritional and therapeutic properties of camel and human milks. International Journal of Genetics and Molecular Biology. 2009; 1:52-58.
Khaskheli M, Arain MA, Chaudhry S, Soomro H, Qureshi TA. Physico chemical quality of camel milk. Journal of Agriculture and Social Sciences. 2005; 2:164-6.
Barłowska J, Litwińczuk Z, Kedzierska-Matysek M, Litwińczuk A. Polymorphism of caprine milk alphas1- casein in relation to performance of four Polish goat breeds. Polish Journal of Veterinary Sciences. 2007; 10:159-164.
Zicarelli L. Buffalo milk: Its properties, dairy yield and mozzarella production. Veterinary Research Communications. 2004; 28:127-35. https://doi.org/10.1023/B:VERC.0000045390.81982.4d DOI: https://doi.org/10.1023/B:VERC.0000045390.81982.4d
El-Agamy EI, Nawar M, Shamsia SM, Awad S, George FW, et al. Are camel milk proteins convenient to the nutrition of cow milk allergic children? Small Ruminant Research. 2009; 82:1-6. https://doi.org/10.1016/j.smallrumres.2008.12.016
Kappeler SR, Farah Z, Puhan Z. 5’-flanking regions of camel milk genes are highly similar to homologue regions of other species and can be divided into two distinct groups. Journal of Dairy Science. 2005; 86:498-508. https://doi.org/10.3168/jds.S0022-0302(03)73628-5 DOI: https://doi.org/10.3168/jds.S0022-0302(03)73628-5
El-Hatmi H, Girardet JM, Gaillard JL, Yahyaouia MH, Attiac H. Characterisation of whey proteins of camel (Camelus dromedarius) milk and colostrum. Small Ruminant Research. 2007; 70:267-71. https://doi.org/10.1016/j.smallrumres.2006.04.001 DOI: https://doi.org/10.1016/j.smallrumres.2006.04.001
Habib HM, Ibrahim WH, Schneider-Stock R, Hassan HM. Camel milk lactoferrin reduces the proliferation of colorectal cancer cells and exerts antioxidant and DNA damage inhibitory activities. Food Chemistry. 2013; 141:148-52. https://doi.org/10.1016/j.foodchem.2013.03.039 DOI: https://doi.org/10.1016/j.foodchem.2013.03.039
Mullaicharam, Christie WW, Clapperton JL. Structures of the Triglycerides of Cow‘S Milk, Fortified Milk (Including Infant Formula) and Human Milk. J Soc Dairy. World J Pharm Sci. 2014; 2:237-242. http://www.FAO.Org/DOCREP/003/X6528/EX6528E00. Htm
Haddadin MS, Gammoh SI, Robinson RK. Seasonal variations in the chemical composition of camel milk in Jordan. Journal of Dairy Research. 2008; 75:8-12. https://doi.org/10.1017/S0022029907002750 DOI: https://doi.org/10.1017/S0022029907002750
Mansson HL. Fatty acids in bovine milk fat. Food and Nutrition Research. 2008; 52. https://doi.org/10.3402/fnr.v52i0.1821 DOI: https://doi.org/10.3402/fnr.v52i0.1821
D’Urso S, Cutrignelli MI, Calabrò S, Bovera F, Tudisco R, et al. Influence of pasture on fatty acid profile of goat milk. Journal of Animal Physiology and Animal Nutrition. 2008; 92:405-10. https://doi.org/10.1111/j.1439-0396.2008.00824.x DOI: https://doi.org/10.1111/j.1439-0396.2008.00824.x
Panwar R, Grover CR, Kumar V, Ranga S, Kumar N. Camel milk: Natural medicine-boon to dairy industry. 2015; 10.
Onjoro P, Schwartz HJ, Njoka EN, Ottaro JM. Effects of mineral status in the soil, forage, water, blood, milk, urine and faeces on milk production of lactating, free-ranging camels in Northern Kenya. Deutscher Tropentag, Göttingen, Germany; 2003. pp. 8-10.
Grant D, Nelson RT, Cannon SB, Shoemaker RC. The USDA-ARS soybean genetics and genomics database. Nucleic Acids Research. 2009; pp. D843-46. https://doi.org/10.1093/nar/gkp798 DOI: https://doi.org/10.1093/nar/gkp798
Mal G, Suchitra SD, Sahani MS. Changes in chemical and macro- minerals content of dromedary milk during lactation. Journal of Camel Practice and Research. 2007; 14:195-197.
Levy A, SteinerL, Yagil R. Camel milk: Disease control and dietary laws. Journal of Health Science. 2013; 1:48-53. https://doi.org/10.17265/2328-7136/2013.12.006 DOI: https://doi.org/10.17265/2328-7136/2013.12.006
Al Haj OA, Al Kanhal HA. Compositional, technological and nutritional aspects of dromedary camel milk. International Dairy Journal. 2010; 20:811-21. https://doi.org/10.1016/j.idairyj.2010.04.003 DOI: https://doi.org/10.1016/j.idairyj.2010.04.003
Eyassu S. Handling, preservation and utilization of camel milk and camel milk products in Shinile and Jijiga Zones, eastern Ethiopia, Eastern Ethiopia. Marketing. 2007; 10:13-7.
Yohannes M, Mekuriaw Z, Gebru G. Potentials of camel production in Babilie and Kebribeyah woredas of the Jijiga Zone, Somali Region, Ethiopia. Livestock Research for Rural Development. 2007; 19.
Mona EY, Ragia OM, Abeer AKH, Mosa TE. Biochemical effects of fermented camel milk on diarrhea in rats. New York Science Journal. 2010; 3.
Conesa C, Sánchez L, Rota C, Pérez MD, Calvo M, et al. Isolation of lactoferrin from milk of different species: calorimetric and antimicrobial studies. Comparative Biochemistry and Physiology Part B. 2008; 150:131-9. https://doi.org/10.1016/j.cbpb.2008.02.005 DOI: https://doi.org/10.1016/j.cbpb.2008.02.005
Yassin MH, Soliman MM, Mostafa SAE, Ali HAM. Antimicrobial effects of camel milk against some bacterial pathogens. Journal of Food And Nutrition Research. 2015; 3:162-8. https://doi.org/10.12691/jfnr-3-3-6 DOI: https://doi.org/10.12691/jfnr-3-3-6
Abdalla KO. An overview of the therapeutic effects of camel milk in the treatment of Type1 diabetes mellitus. Biomolecular Research and Therapeutics. 2014.
Agrawal RP, Jain S, Shah S, Chopra A, Agarwal V. Effect of camel milk on glycemic control and insulin requirement in patients with Type 1 diabetes: 2-years randomized controlled trial. European Journal of Clinical Nutrition. 2011; 65:1048-1052. https://doi.org/10.1038/ejcn.2011.98 DOI: https://doi.org/10.1038/ejcn.2011.98
Khan AA, Alzohairy M. Hepatoprotective effects of camel milk against CCl4-induced hepatotoxicity in rats. Asian Journal of Biochemistry. 2011; 6:171-80. https://doi.org/10.3923/ajb.2011.171.180 DOI: https://doi.org/10.3923/ajb.2011.171.180
Agrawal RP, Tantia P, Jain S, Agrawal R, Agrawal V. Camel milk: A possible boon for Type 1 diabetic patients. Cellular and Molecular Biology. 2013; 59:99-107.
Al-Majali AM, Ismail ZB, Al-Hami Y. Lactoferrin concentration in milk from camels (Camelus dromedarius) with and without subclinical mastitis. International Journal of Applied Research in Veterinary Medicine. 2007; 5:120.
Jenssen H, Hancock RE. Antimicrobial Properties of Lactoferrin. Biochimie. 2009; 91:19-29. https://doi.org/10.1016/j.biochi.2008.05.015 DOI: https://doi.org/10.1016/j.biochi.2008.05.015
Benkerroum N, Mekkaoui M, Bennani N, Hidane K. Antimicrobial activity of camel’s milk against pathogenic strains of Escherichia coli and Listeria monocytogenes. International Journal of Dairy Technology. 2004; 57:39-43. https://doi.org/10.1111/j.1471-0307.2004.00127.x DOI: https://doi.org/10.1111/j.1471-0307.2004.00127.x
Yagil R. Camel Milk And Its Unique Anti-Diarrheal Properties. The Israel Medical Association Journal. 2013; 15:35-36.
Greenberg HB, Estes MK. Rotaviruses: From pathogenesis to vaccination. Gastroenterology. 2009; 136:1939-1951. https://doi.org/10.1053/j.gastro.2009.02.076 DOI: https://doi.org/10.1053/j.gastro.2009.02.076
Jrad Z, El Hatmi H, Adt I, Khorchani T, Degraev P, et al. Antimicrobial activity of camel milk casein and its hydrolysates. Actaalimentaria. 2015; 44:609-16. https://doi.org/10.1556/066.2015.44.0034 DOI: https://doi.org/10.1556/066.2015.44.0034
Alluwaimi AM. The Etiology of Mycobacterium avium Subspecies Paratuberculosis in Crohn’s Disease. Saudi Med J. 2017; 28:1479-1484.
Shabo YR, Barzel, Yagil R. Etiology of Crohn’s disease and camel milk treatment. Journal of Camel Practice and Research. 2008; 15:55-9.
Reichelt KL, Knivsbergam AM Can the pathophysiology of autism be explained by the nature of the discovered urine peptides? Nutritional Neuroscience. 2003; 6:19-28. https://doi.org/10.1080/1028415021000042839 DOI: https://doi.org/10.1080/1028415021000042839
El-Agamy EI, Nawar M, Shamsia SM, Awad S, George FW, et al. Are camel milk proteins convenient to the nutrition of cow milk allergic children? Small Ruminant Research. 2009; 82:1-6. https://doi.org/10.1016/j.smallrumres.2008.12.016 DOI: https://doi.org/10.1016/j.smallrumres.2008.12.016
De Almeida RR. Camel milk. Characteristics and perspectives for use in clinical practice. Revista Chilena de Nutricion. 2011; 38:211-18. https://doi.org/10.4067/S0717-75182011000200011 DOI: https://doi.org/10.4067/S0717-75182011000200011
Ehlayel MS, Hazeima KA, Al-Mesaifri F, Bener A. Camel milk: An alternative for cow’s milk allergy in children. Allergy and Asthma Proceedings. 2011; 32:255-8. https://doi.org/10.2500/aap.2011.32.3429 DOI: https://doi.org/10.2500/aap.2011.32.3429
Salwa MQ, Lina AF. Antigenotoxic and anticytotoxic effect of camel milk in mice treated with cisplatin. Saudi Journal of Biological Sciences. 2010; 17:159-66. https://doi.org/10.1016/j.sjbs.2010.02.010 DOI: https://doi.org/10.1016/j.sjbs.2010.02.010
Traber MG, Stevens JF. Vitamins C and E: Beneficial effects from a mechanistic perspective. Free Radical Biology and Medicine. 2011; 51:1000-13. https://doi.org/10.1016/j.freeradbiomed.2011.05.017 DOI: https://doi.org/10.1016/j.freeradbiomed.2011.05.017
Markiewicz-Górka I, Zawadzki M, Januszewska L, Hombek-Urban K, Pawlas K. Influence of selenium and/or magnesium on alleviation alcohol induced oxidative stress in rats, normalization function of liver and changes in serum lipid parameters. Human and Experimental Toxicology. 2011; 30:1811-27. https://doi.org/10.1177/0960327111401049 DOI: https://doi.org/10.1177/0960327111401049
Salami M, Moosavi-Movahedi AA, Moosavi-Movahedi F, Ehsani MR, Yousefi R, et al. Biological activity of camel milk casein following enzymatic digestion. Journal of Dairy Research. 2011; 78:471-8. https://doi.org/10.1017/S0022029911000628 DOI: https://doi.org/10.1017/S0022029911000628
Baumann L. Skin ageing and its treatment. The Journal of Pathology. 2007; 211:241-51.https://doi.org/10.1002/path.2098 DOI: https://doi.org/10.1002/path.2098
Saltanat H, Li H, Xu Y, Wang J, Liu F, et al. The influences of camel milk on the immune response of chronic hepatitis B patients. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2009; 25:431-3.
Redwan el-RM, Tabll A. Camel lactoferrin markedly inhibits hepatitis C virus genotype 4 infection of human peripheral blood leukocytes. Journal of Immunoassay and Immunochemistry. 2007; 28:267-77. https://doi.org/10.1080/15321810701454839 DOI: https://doi.org/10.1080/15321810701454839
Maghraby AS, Mohamed MA, Abdel-Salam AM. Anti-schistosomal activity of colostral and mature camel milk on Schistosoma mansoni infected mice. Asia Pacific Journal of Clinical Nutrition. 2005; 14:432-8.
Choi SK, Park KD, Kim DA, Lee DW, Kim YJ. Preparation of camel milk liposome and its anti-aging effects. Journal of the Society of Cosmetic Scientists of Korea. 2013; 40:155-61. https://doi.org/10.15230/SCSK.2014.40.2.155 DOI: https://doi.org/10.15230/SCSK.2014.40.2.155
Adlerova L, Bartoskova A, Faldyna M. Lactoferrin: A Review. Veterinarni Medicina. 2008; 53:457-68. https://doi.org/10.17221/1978-VETMED DOI: https://doi.org/10.17221/1978-VETMED